MP-Institute Colloquium

Particle technology plays a pivotal role in addressing critical challenges in drug product manufacturing, particularly for compounds with poor solubility and permeability. This presentation bridges granular materials science and pharmaceutical applications, focusing on three key areas. First, we outline the persistent hurdles in drug development, where inadequate solubility and permeability limit bioavailability, necessitating advanced particle engineering strategies. Second, we explore bulk solids and particle characterization techniques that inform robust formulation design and scalable manufacturing processes. Finally, we highlight the integration of predictive computational methods, such as Discrete Element Method (DEM) simulations, for virtual prototyping of drug formulations. This talk aims to bridge the gap between the material science of granular matter and drug product design to open a pathway to impact healthcare through interdisciplinary collaboration.